SIRT6 transcriptionally regulates global protein synthesis through transcription factor Sp1 independent of its deacetylase activity

Global protein synthesis is emerging as an important player in the context of aging and age-related diseases. However, the intricate molecular networks that regulate protein synthesis are poorly understood. Here, we report that SIRT6, a nuclear-localized histone deacetylase represses global protein...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Ravi, Venkatraman, Jain, Aditi, Khan, Danish, Ahamed, Faiz, Mishra, Sneha, Giri, Malyasree, Inbaraj, Meena, Krishna, Swati, Sarikhani, Mohsen, Maity, Sangeeta, Kumar, Shweta, Shah, Riyaz Ahmad, Dave, Pratik, Pandit, Anwit S, Rajendran, Rajprabu, Desingu, Perumal A, Varshney, Umesh, Das, Saumitra, Kolthur-Seetharam, Ullas, Rajakumari, Sona, Singh, Mahavir, Sundaresan, Nagalingam R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Gene regulation, Chromatin and Epigenetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755095/
https://ncbi.nlm.nih.gov/pubmed/31372634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz648
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