SIRT6 transcriptionally regulates global protein synthesis through transcription factor Sp1 independent of its deacetylase activity

Global protein synthesis is emerging as an important player in the context of aging and age-related diseases. However, the intricate molecular networks that regulate protein synthesis are poorly understood. Here, we report that SIRT6, a nuclear-localized histone deacetylase represses global protein...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nucleic Acids Res
Main Authors: Ravi, Venkatraman, Jain, Aditi, Khan, Danish, Ahamed, Faiz, Mishra, Sneha, Giri, Malyasree, Inbaraj, Meena, Krishna, Swati, Sarikhani, Mohsen, Maity, Sangeeta, Kumar, Shweta, Shah, Riyaz Ahmad, Dave, Pratik, Pandit, Anwit S, Rajendran, Rajprabu, Desingu, Perumal A, Varshney, Umesh, Das, Saumitra, Kolthur-Seetharam, Ullas, Rajakumari, Sona, Singh, Mahavir, Sundaresan, Nagalingam R
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2019
נושאים:
Gene regulation, Chromatin and Epigenetics
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755095/
https://ncbi.nlm.nih.gov/pubmed/31372634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz648
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