N-acetylcysteine and vitamin E rescue animal longevity and cellular oxidative stress in preclinical models of mitochondrial complex I disease

Oxidative stress is a known contributing factor in mitochondrial respiratory chain (RC) disease pathogenesis. Yet, no efficient means exists to objectively evaluate the comparative therapeutic efficacy or toxicity of different antioxidant compounds empirically used in human RC disease. We postulated...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Mol Genet Metab
Huvudupphovsmän: Polyak, Erzsebet, Ostrovsky, Julian, Peng, Min, Dingley, Stephen D., Tsukikawa, Mai, Kwon, Young Joon, McCormack, Shana, Bennett, Michael, Xiao, Rui, Seiler, Christoph, Zhang, Zhe, Falk, Marni J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891356/
https://ncbi.nlm.nih.gov/pubmed/29526616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2018.02.013
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk