Primary Respiratory Chain Disease Causes Tissue-Specific Dysregulation of the Global Transcriptome and Nutrient-Sensing Signaling Network

Primary mitochondrial respiratory chain (RC) diseases are heterogeneous in etiology and manifestations but collectively impair cellular energy metabolism. Mechanism(s) by which RC dysfunction causes global cellular sequelae are poorly understood. To identify a common cellular response to RC disease,...

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Detalhes bibliográficos
Main Authors: Zhang, Zhe, Tsukikawa, Mai, Peng, Min, Polyak, Erzsebet, Nakamaru-Ogiso, Eiko, Ostrovsky, Julian, McCormack, Shana, Place, Emily, Clarke, Colleen, Reiner, Gail, McCormick, Elizabeth, Rappaport, Eric, Haas, Richard, Baur, Joseph A., Falk, Marni J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722174/
https://ncbi.nlm.nih.gov/pubmed/23894440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069282
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