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Rbfox1 Regulates Synaptic Transmission Through the Inhibitory Neuron Specific vSNARE Vamp1
Dysfunction of the neuronal RNA binding protein RBFOX1 has been linked to epilepsy and autism spectrum disorders. Rbfox1 loss in mice leads to neuronal hyper-excitability and seizures, but the physiological basis for this is unknown. We identify the vSNARE protein Vamp1 as a major Rbfox1 target. Vam...
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| Yayımlandı: | Neuron |
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| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5890944/ https://ncbi.nlm.nih.gov/pubmed/29621484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.03.008 |
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