Cytoplasmic Rbfox1 regulates the expression of synaptic and autism-related genes

Human genetic studies have identified the neuronal RNA binding protein, Rbfox1, as a candidate gene for autism spectrum disorders. While Rbfox1 functions as a splicing regulator in the nucleus, it is also alternatively spliced to produce cytoplasmic isoforms. To investigate the function of cytoplasm...

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Publicat a:Neuron
Autors principals: Lee, Ji-Ann, Damianov, Andrey, Lin, Chia-Ho, Fontes, Mariana, Parikshak, Neelroop N., Anderson, Erik S., Geschwind, Daniel H., Black, Douglas L., Martin, Kelsey C.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858412/
https://ncbi.nlm.nih.gov/pubmed/26687839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.11.025
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