Rbfox1 Regulates Synaptic Transmission Through the Inhibitory Neuron Specific vSNARE Vamp1

Dysfunction of the neuronal RNA binding protein RBFOX1 has been linked to epilepsy and autism spectrum disorders. Rbfox1 loss in mice leads to neuronal hyper-excitability and seizures, but the physiological basis for this is unknown. We identify the vSNARE protein Vamp1 as a major Rbfox1 target. Vam...

詳細記述

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書誌詳細
出版年:Neuron
主要な著者: Vuong, Celine K., Wei, Weizheng, Lee, Ji-Ann, Lin, Chia-Ho, Damianov, Andrey, de la Torre-Ubieta, Luis, Halabi, Reem, Otis, Klara Olofsdotter, Martin, Kelsey C., O’Dell, Thomas J., Black, Douglas L.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890944/
https://ncbi.nlm.nih.gov/pubmed/29621484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.03.008
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