Minocycline attenuates colistin-induced neurotoxicity via suppression of apoptosis, mitochondrial dysfunction and oxidative stress

Background: Neurotoxicity is an adverse effect patients experience during colistin therapy. The development of effective neuroprotective agents that can be co-administered during polymyxin therapy remains a priority area in antimicrobial chemotherapy. The present study investigates the neuroprotecti...

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Vydáno v:J Antimicrob Chemother
Hlavní autoři: Dai, Chongshan, Ciccotosto, Giuseppe D., Cappai, Roberto, Wang, Yang, Tang, Shusheng, Xiao, Xilong, Velkov, Tony
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890749/
https://ncbi.nlm.nih.gov/pubmed/28204513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx037
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