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Baicalein acts as a nephroprotectant that ameliorates colistin-induced nephrotoxicity by activating the antioxidant defence mechanism of the kidneys and down-regulating the inflammatory response
BACKGROUND: Nephrotoxicity is the major adverse effect patients experience during colistin therapy. The development of effective nephroprotective agents that can be co-administered during polymyxin therapy remains a priority area in antimicrobial chemotherapy. OBJECTIVES: To investigate the nephropr...
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| Publicado no: | J Antimicrob Chemother |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5890707/ https://ncbi.nlm.nih.gov/pubmed/28859441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx185 |
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