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Colistin-Induced Nephrotoxicity in Mice Involves the Mitochondrial, Death Receptor, and Endoplasmic Reticulum Pathways

Nephrotoxicity is the dose-limiting factor for colistin, but the exact mechanism is unknown. This study aimed to investigate the roles of the mitochondrial, death receptor, and endoplasmic reticulum pathways in colistin-induced nephrotoxicity. Mice were intravenously administered 7.5 or 15 mg of col...

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Bibliografiske detaljer
Main Authors: Dai, Chongshan, Li, Jichang, Tang, Shusheng, Li, Jian, Xiao, Xilong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068542/
https://ncbi.nlm.nih.gov/pubmed/24798292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00070-14
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