Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis

This is the first study to investigate the hepatoprotective effect of CQ on acute liver injury caused by carbon tetrachloride (CCl(4)) in a murine model and the underlying molecular mechanisms. Ninety-six mice were randomly divided into the control (n = 8), CQ (n = 8), CCl(4) (n = 40), and CCl(4) + ...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Dai, Chongshan, Xiao, Xilong, Li, Daowen, Tun, Sun, Wang, Ying, Velkov, Tony, Tang, Shusheng
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255886/
https://ncbi.nlm.nih.gov/pubmed/30478280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1136-2
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