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Alzheimer’s disease genetics and ABCA7 splicing

Both common and rare polymorphisms within ABCA7 have been associated with Alzheimer’s disease (AD). In particular, the rare AD associated polymorphism rs200538373 was associated with altered ABCA7 exon 41 splicing and an AD risk odds ratio of ~1.9. To probe the role of this polymorphism in ABCA7 spl...

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Bibliografiska uppgifter
I publikationen:J Alzheimers Dis
Huvudupphovsmän: Vasquez, Jared B., Simpson, James F., Harpole, Ryan, Estus, Steven
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890296/
https://ncbi.nlm.nih.gov/pubmed/28655137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170872
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