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Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal
The folding and insertion of integral β-barrel membrane proteins into the outer membrane of Gram-negative bacteria is required for viability and bacterial pathogenesis. Unfortunately, the lack of selective and potent modulators to dissect β-barrel folding in vivo has hampered our understanding of th...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5889671/ https://ncbi.nlm.nih.gov/pubmed/29555747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800043115 |
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