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Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal

The folding and insertion of integral β-barrel membrane proteins into the outer membrane of Gram-negative bacteria is required for viability and bacterial pathogenesis. Unfortunately, the lack of selective and potent modulators to dissect β-barrel folding in vivo has hampered our understanding of th...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Storek, Kelly M., Auerbach, Marcy R., Shi, Handuo, Garcia, Natalie K., Sun, Dawei, Nickerson, Nicholas N., Vij, Rajesh, Lin, Zhonghua, Chiang, Nancy, Schneider, Kellen, Wecksler, Aaron T., Skippington, Elizabeth, Nakamura, Gerald, Seshasayee, Dhaya, Koerber, James T., Payandeh, Jian, Smith, Peter A., Rutherford, Steven T.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889671/
https://ncbi.nlm.nih.gov/pubmed/29555747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800043115
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