Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal

The folding and insertion of integral β-barrel membrane proteins into the outer membrane of Gram-negative bacteria is required for viability and bacterial pathogenesis. Unfortunately, the lack of selective and potent modulators to dissect β-barrel folding in vivo has hampered our understanding of th...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Storek, Kelly M., Auerbach, Marcy R., Shi, Handuo, Garcia, Natalie K., Sun, Dawei, Nickerson, Nicholas N., Vij, Rajesh, Lin, Zhonghua, Chiang, Nancy, Schneider, Kellen, Wecksler, Aaron T., Skippington, Elizabeth, Nakamura, Gerald, Seshasayee, Dhaya, Koerber, James T., Payandeh, Jian, Smith, Peter A., Rutherford, Steven T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889671/
https://ncbi.nlm.nih.gov/pubmed/29555747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800043115
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