Characterization of clinically used oral antiseptics as quadruplex-binding ligands

Approaches to characterize the nucleic acid-binding properties of drugs and druglike small molecules are crucial to understanding the behavior of these compounds in cellular systems. Here, we use a Small Molecule Microarray (SMM) profiling approach to identify the preferential interaction between ch...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Calabrese, David R, Zlotkowski, Katherine, Alden, Stephanie, Hewitt, William M, Connelly, Colleen M, Wilson, Robert M, Gaikwad, Snehal, Chen, Lu, Guha, Rajarshi, Thomas, Craig J, Mock, Beverly A, Schneekloth, John S
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
Assuntos:
Chemical Biology and Nucleic Acid Chemistry
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888870/
https://ncbi.nlm.nih.gov/pubmed/29481610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky084
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