लोड हो रहा है...
A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma
SIMPLE SUMMARY: The DNA G-quadruplex (G4) present in the promoter of the MYC oncogene, commonly amplified in cancers, including multiple myeloma, represents a potential anti-cancer target. A previously identified MYC G4-stablizer, which demonstrated cytotoxicity and senescence in myeloma cells, was...
में बचाया:
| में प्रकाशित: | Cancers (Basel) |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
MDPI
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7650714/ https://ncbi.nlm.nih.gov/pubmed/33066043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102952 |
| टैग : |
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