The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia

Animals require an immediate response to oxygen availability to allow rapid shifts between oxidative and glycolytic metabolism. These metabolic shifts are highly regulated by the HIF transcription factor. The factor inhibiting HIF (FIH) is an asparaginyl hydroxylase that controls HIF transcriptional...

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Bibliografske podrobnosti
izdano v:Cell Metab
Main Authors: Sim, Jingwei, Cowburn, Andrew S., Palazon, Asis, Madhu, Basetti, Tyrakis, Petros A., Macías, David, Bargiela, David M., Pietsch, Sandra, Gralla, Michael, Evans, Colin E., Kittipassorn, Thaksaon, Chey, Yu C.J., Branco, Cristina M., Rundqvist, Helene, Peet, Daniel J., Johnson, Randall S.
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887987/
https://ncbi.nlm.nih.gov/pubmed/29617647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.02.020
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