The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia

Animals require an immediate response to oxygen availability to allow rapid shifts between oxidative and glycolytic metabolism. These metabolic shifts are highly regulated by the HIF transcription factor. The factor inhibiting HIF (FIH) is an asparaginyl hydroxylase that controls HIF transcriptional...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Metab
Prif Awduron: Sim, Jingwei, Cowburn, Andrew S., Palazon, Asis, Madhu, Basetti, Tyrakis, Petros A., Macías, David, Bargiela, David M., Pietsch, Sandra, Gralla, Michael, Evans, Colin E., Kittipassorn, Thaksaon, Chey, Yu C.J., Branco, Cristina M., Rundqvist, Helene, Peet, Daniel J., Johnson, Randall S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cell Press 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887987/
https://ncbi.nlm.nih.gov/pubmed/29617647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.02.020
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