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Structure of the Insulin Receptor-Insulin Complex by Single Particle CryoEM analysis
The insulin receptor (IR) is a dimeric protein that plays a crucial role in controlling glucose homeostasis, regulating lipid, protein and carbohydrate metabolism, and modulating brain neurotransmitter levels(1,2). IR dysfunctions have been associated with many diseases, including diabetes, cancer,...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5886813/ https://ncbi.nlm.nih.gov/pubmed/29512653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature26153 |
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