Structure of the Insulin Receptor-Insulin Complex by Single Particle CryoEM analysis

The insulin receptor (IR) is a dimeric protein that plays a crucial role in controlling glucose homeostasis, regulating lipid, protein and carbohydrate metabolism, and modulating brain neurotransmitter levels(1,2). IR dysfunctions have been associated with many diseases, including diabetes, cancer,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nature
मुख्य लेखकों: Scapin, Giovanna, Dandey, Venkata P., Zhang, Zhening, Prosise, Winifred, Hruza, Alan, Kelly, Theresa, Mayhood, Todd, Strickland, Corey, Potter, Clinton S., Carragher, Bridget
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886813/
https://ncbi.nlm.nih.gov/pubmed/29512653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature26153
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