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Inhibition of antigen presentation during AAV gene therapy using virus peptides
The clinical trial using adeno-associated virus (AAV) vector delivery of mini-dystrophin in patients with Duchenne Muscular Dystrophy (DMD) demonstrated a cytotoxic lymphocyte (CTL) response targeting the transgene product. These mini-dystrophin-specific T-cells have the potential to clear all trans...
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| Publicado en: | Hum Mol Genet |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5886241/ https://ncbi.nlm.nih.gov/pubmed/29272432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx427 |
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