Neurofibromatosis type 1 alternative splicing is a key regulator of Ras/ERK signaling and learning behaviors in mice

Appropriate activation of the Ras/extracellular signal-regulated kinase (ERK) protein signaling cascade within the brain is crucial for optimal learning and memory. One key regulator of this cascade is the Nf1 Ras GTPase activating protein (RasGAP), which attenuates Ras/ERK signaling by converting a...

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Bibliografische gegevens
Gepubliceerd in:Hum Mol Genet
Hoofdauteurs: Nguyen, Hieu T., Hinman, Melissa N., Guo, Xuan, Sharma, Alok, Arakawa, Hiroyuki, Luo, Guangbin, Lou, Hua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886178/
https://ncbi.nlm.nih.gov/pubmed/28934393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx264
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