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Neurofibromatosis type 1 alternative splicing is a key regulator of Ras/ERK signaling and learning behaviors in mice

Appropriate activation of the Ras/extracellular signal-regulated kinase (ERK) protein signaling cascade within the brain is crucial for optimal learning and memory. One key regulator of this cascade is the Nf1 Ras GTPase activating protein (RasGAP), which attenuates Ras/ERK signaling by converting a...

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Bibliografiske detaljer
Udgivet i:Hum Mol Genet
Main Authors: Nguyen, Hieu T., Hinman, Melissa N., Guo, Xuan, Sharma, Alok, Arakawa, Hiroyuki, Luo, Guangbin, Lou, Hua
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886178/
https://ncbi.nlm.nih.gov/pubmed/28934393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx264
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