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Calcium-mediated histone modifications regulate alternative splicing in cardiomyocytes
In cardiomyocytes, calcium is known to control gene expression at the level of transcription, whereas its role in regulating alternative splicing has not been explored. Here we report that, in mouse primary or embryonic stem cell-derived cardiomyocytes, increased calcium levels induce robust and rev...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246288/ https://ncbi.nlm.nih.gov/pubmed/25368158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408964111 |
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