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Calcium-mediated histone modifications regulate alternative splicing in cardiomyocytes

In cardiomyocytes, calcium is known to control gene expression at the level of transcription, whereas its role in regulating alternative splicing has not been explored. Here we report that, in mouse primary or embryonic stem cell-derived cardiomyocytes, increased calcium levels induce robust and rev...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Sharma, Alok, Nguyen, Hieu, Geng, Cuiyu, Hinman, Melissa N., Luo, Guangbin, Lou, Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246288/
https://ncbi.nlm.nih.gov/pubmed/25368158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408964111
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