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Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner

Recent studies have provided strong evidence for a regulatory link among chromatin structure, histone modification, and splicing regulation. However, it is largely unknown how local histone modification patterns surrounding alternative exons are connected to differential alternative splicing outcome...

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Detalhes bibliográficos
Main Authors: Zhou, Hua-Lin, Hinman, Melissa N., Barron, Victoria A., Geng, Cuiyu, Zhou, Guangjin, Luo, Guangbin, Siegel, Ruth E., Lou, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169152/
https://ncbi.nlm.nih.gov/pubmed/21808035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103344108
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