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All three RNA recognition motifs and the hinge region of HuC play distinct roles in the regulation of alternative splicing

The four Hu [embryonic lethal abnormal vision-like (ELAVL)] protein family members regulate alternative splicing by binding to U-rich sequences surrounding target exons and affecting the interaction of the splicing machinery and/or local chromatin modifications. Each of the Hu proteins contains a di...

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Detalles Bibliográficos
Main Authors: Hinman, Melissa N., Zhou, Hua-Lin, Sharma, Alok, Lou, Hua
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643579/
https://ncbi.nlm.nih.gov/pubmed/23525460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt166
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