Loading...

Neurofibromatosis Type 1 Alternative Splicing Is a Key Regulator of Ras Signaling in Neurons

Neurofibromatosis type I (Nf1) is a GTPase-activating protein (GAP) that inactivates the oncoprotein Ras and plays important roles in nervous system development and learning. Alternative exon 23a falls within the Nf1 GAP domain coding sequence and is tightly regulated in favor of skipping in neurons...

Full description

Saved in:
Bibliographic Details
Main Authors: Hinman, Melissa N., Sharma, Alok, Luo, Guangbin, Lou, Hua
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054297/
https://ncbi.nlm.nih.gov/pubmed/24710274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00019-14
Tags: Add Tag
No Tags, Be the first to tag this record!