Attraction and Compaction of Migratory Breast Cancer Cells by Bone Matrix Proteins through Tumor-Osteocyte Interactions

Bone is a frequent site of metastasis from breast cancer. To understand the potential role of osteocytes in bone metastasis, we investigated tumor-osteocyte interactions using two cell lines derived from the MDA-MB-231 breast cancer cells, primary breast cancer cells, and MLO-A5/MLO-Y4 osteocyte cel...

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Udgivet i:Sci Rep
Main Authors: Chen, Andy, Wang, Luqi, Liu, Shengzhi, Wang, Yue, Liu, Yunlong, Wang, Mu, Nakshatri, Harikrishna, Li, Bai-Yan, Yokota, Hiroki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882940/
https://ncbi.nlm.nih.gov/pubmed/29615735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23833-1
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