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Reduction in Migratory Phenotype in a Metastasized Breast Cancer Cell Line via Downregulation of S100A4 and GRM3

To investigate phenotypic and genotypic alterations before and after bone metastasis, we conducted genome-wide mRNA profiling and DNA exon sequencing of two cell lines (TMD and BMD) derived from a mouse xenograft model. TMD cells were harvested from the mammary fat pad after transfecting MDA-MB-231...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Andy, Wang, Luqi, Li, Bai-Yan, Sherman, Jesse, Ryu, Jong E., Hamamura, Kazunori, Liu, Yunlong, Nakshatri, Harikrishna, Yokota, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471271/
https://ncbi.nlm.nih.gov/pubmed/28615627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03811-9
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