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Guanabenz Downregulates Inflammatory Responses via eIF2α Dependent and Independent Signaling
Integrated stress responses (ISR) may lead to cell death and tissue degeneration via eukaryotic translation initiation factor 2 α (eIF2α)-mediated signaling. Alleviating ISR by modulating eIF2α phosphorylation can reduce the symptoms associated with various diseases. Guanabenz is known to elevate th...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4881500/ https://ncbi.nlm.nih.gov/pubmed/27164082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050674 |
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