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Predicting and validating the pathway of Wnt3a-driven suppression of osteoclastogenesis

Wnt signaling plays a major role in bone homeostasis and mechanotransduction, but its role and regulatory mechanism in osteoclast development are not fully understood. Through genome-wide in silico analysis, we examined Wnt3a-driven regulation of osteoclast development. Mouse bone marrow-derived cel...

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Détails bibliographiques
Auteurs principaux: Hamamura, Kazunori, Chen, Andy, Nishimura, Akinobu, Tanjung, Nancy, Sudo, Akihiro, Yokota, Hiroki
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187210/
https://ncbi.nlm.nih.gov/pubmed/25038457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.07.018
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