Blocking distinct interactions between Glioblastoma cells and their tissue microenvironment: A novel multi-targeted therapeutic approach

Due to the highly invasive nature of Glioblastoma (GB), complete surgical resection is not feasible, while motile tumour cells are often associated with several specific brain structures that enhance treatment-resistance. Here, we investigate the therapeutic potential of Disulfiram and Carbenoxolone...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mettang, Melanie, Meyer-Pannwitt, Viola, Karpel-Massler, Georg, Zhou, Shaoxia, Carragher, Neil O., Föhr, Karl Josef, Baumann, Bernd, Nonnenmacher, Lisa, Enzenmüller, Stefanie, Dahlhaus, Meike, Siegelin, Markus D., Stroh, Sebastien, Mertens, Daniel, Fischer-Posovszky, Pamela, Schneider, E. Marion, Halatsch, Marc-Eric, Debatin, Klaus-Michael, Westhoff, Mike-Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882900/
https://ncbi.nlm.nih.gov/pubmed/29615749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23592-z
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