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A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy
Glioblastoma multiforme (GBM) is the most common primary brain tumor and among the most difficult to treat malignancies per se. In almost 90% of all GBM alterations in the PI3K/Akt/mTOR have been found, making this survival cascade a promising therapeutic target, particular for combination therapy t...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4488267/ https://ncbi.nlm.nih.gov/pubmed/26121251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131670 |
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