The effects of PI3K-mediated signalling on glioblastoma cell behaviour

The PI3K/Akt/mTOR signalling network is activated in almost 90% of all glioblastoma, the most common primary brain tumour, which is almost invariably lethal within 15 months of diagnosis. Despite intensive research, modulation of this signalling cascade has so far yielded little therapeutic benefit,...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncogenesis
Auteurs principaux: Langhans, Julia, Schneele, Lukas, Trenkler, Nancy, von Bandemer, Hélène, Nonnenmacher, Lisa, Karpel-Massler, Georg, Siegelin, Markus D., Zhou, Shaoxia, Halatsch, Marc-Eric, Debatin, Klaus-Michael, Westhoff, Mike-Andrew
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Brief Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868055/
https://ncbi.nlm.nih.gov/pubmed/29184057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-017-0004-8
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