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The effects of PI3K-mediated signalling on glioblastoma cell behaviour
The PI3K/Akt/mTOR signalling network is activated in almost 90% of all glioblastoma, the most common primary brain tumour, which is almost invariably lethal within 15 months of diagnosis. Despite intensive research, modulation of this signalling cascade has so far yielded little therapeutic benefit,...
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| Pubblicato in: | Oncogenesis |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5868055/ https://ncbi.nlm.nih.gov/pubmed/29184057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-017-0004-8 |
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