A critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapy

Members of the PI3K/Akt/mTor signaling cascade are among the most frequently altered proteins in cancer, yet the therapeutic application of pharmacological inhibitors of this signaling network, either as monotherapy or in combination therapy (CT) has so far not been particularly successful. In this...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Ther
Asıl Yazarlar: Westhoff, Mike-Andrew, Karpel-Massler, Georg, Brühl, Oliver, Enzenmüller, Stefanie, La Ferla-Brühl, Katia, Siegelin, Markus D, Nonnenmacher, Lisa, Debatin, Klaus-Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452069/
https://ncbi.nlm.nih.gov/pubmed/26056598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2052-8426-2-32
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