A critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapy

Members of the PI3K/Akt/mTor signaling cascade are among the most frequently altered proteins in cancer, yet the therapeutic application of pharmacological inhibitors of this signaling network, either as monotherapy or in combination therapy (CT) has so far not been particularly successful. In this...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Ther
Prif Awduron: Westhoff, Mike-Andrew, Karpel-Massler, Georg, Brühl, Oliver, Enzenmüller, Stefanie, La Ferla-Brühl, Katia, Siegelin, Markus D, Nonnenmacher, Lisa, Debatin, Klaus-Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Review
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452069/
https://ncbi.nlm.nih.gov/pubmed/26056598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2052-8426-2-32
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg