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The effects of PI3K-mediated signalling on glioblastoma cell behaviour

The PI3K/Akt/mTOR signalling network is activated in almost 90% of all glioblastoma, the most common primary brain tumour, which is almost invariably lethal within 15 months of diagnosis. Despite intensive research, modulation of this signalling cascade has so far yielded little therapeutic benefit,...

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Bibliografische gegevens
Gepubliceerd in:Oncogenesis
Hoofdauteurs: Langhans, Julia, Schneele, Lukas, Trenkler, Nancy, von Bandemer, Hélène, Nonnenmacher, Lisa, Karpel-Massler, Georg, Siegelin, Markus D., Zhou, Shaoxia, Halatsch, Marc-Eric, Debatin, Klaus-Michael, Westhoff, Mike-Andrew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868055/
https://ncbi.nlm.nih.gov/pubmed/29184057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-017-0004-8
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