Загрузка...
Structure-activity relationships among DNA ligase inhibitors; characterization of a selective uncompetitive DNA ligase I inhibitor
In human cells, there are three genes that encode DNA ligase polypeptides with distinct but overlapping functions. Previously small molecule inhibitors of human DNA ligases were identified using a structure-based approach. Three of these inhibitors, L82, a DNA ligase I (LigI)-selective inhibitor, an...
Сохранить в:
| Опубликовано в: : | DNA Repair (Amst) |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881949/ https://ncbi.nlm.nih.gov/pubmed/29078112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.10.002 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|