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Structural insights into the U-box, a domain associated with multi-ubiquitination

The structure of the U-box in the essential Saccharomyces cerevisiae pre-mRNA splicing factor Prp19p has been determined by NMR. The conserved zinc-binding sites supporting the cross-brace arrangement in RING-finger domains are replaced by hydrogen-bonding networks in the U-box. These hydrogen-bondi...

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Detalhes bibliográficos
Publicado no:Nat Struct Biol
Main Authors: Ohi, Melanie D., Vander Kooi, Craig W., Rosenberg, Joshua A., Chazin, Walter J., Gould, Kathleen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881891/
https://ncbi.nlm.nih.gov/pubmed/12627222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsb906
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