Structural and Functional Analysis of Essential pre-mRNA Splicing Factor Prp19p

U-box-containing Prp19p is an integral component of the Prp19p-associated complex (the nineteen complex, or NTC) that is essential for activation of the spliceosome. Prp19p makes numerous protein-protein contacts with other NTC components and is required for NTC stability. Here we show that Prp19p f...

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Detalhes bibliográficos
Main Authors: Ohi, Melanie D., Kooi, Craig W. Vander, Rosenberg, Joshua A., Ren, Liping, Hirsch, Justin P., Chazin, Walter J., Walz, Thomas, Gould, Kathleen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538785/
https://ncbi.nlm.nih.gov/pubmed/15601865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.1.451-460.2005
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