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Structural and functional characterization of the monomeric U-box domain from E4B
Substantial evidence has accumulated indicating a significant role for oligomerization in the function of E3 ubiquitin ligases. Among the many characterized E3 ligases, the yeast U-box protein Ufd2 and its mammalian homolog E4B appear to be unique in functioning as monomers. An E4B U-box domain cons...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806929/ https://ncbi.nlm.nih.gov/pubmed/20017557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901620v |
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