Structural and functional characterization of the monomeric U-box domain from E4B

Substantial evidence has accumulated indicating a significant role for oligomerization in the function of E3 ubiquitin ligases. Among the many characterized E3 ligases, the yeast U-box protein Ufd2 and its mammalian homolog E4B appear to be unique in functioning as monomers. An E4B U-box domain cons...

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Main Authors: Nordquist, Kyle A., Dimitrova, Yoana N., Brzovic, Peter S., Ridenour, Whitney B., Munro, Kim A., Soss, Sarah E., Caprioli, Richard M., Klevit, Rachel E., Chazin, Walter J.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806929/
https://ncbi.nlm.nih.gov/pubmed/20017557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901620v
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