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Structural characterization of the fission yeast U5.U2/U6 spliceosome complex
The spliceosome is a dynamic macromolecular machine that catalyzes the excision of introns from pre-mRNA. The megadalton-sized spliceosome is composed of four small nuclear RNPs and additional pre-mRNA splicing factors. The formation of an active spliceosome involves a series of regulated steps that...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1805518/ https://ncbi.nlm.nih.gov/pubmed/17360628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611591104 |
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