Structural characterization of the fission yeast U5.U2/U6 spliceosome complex

The spliceosome is a dynamic macromolecular machine that catalyzes the excision of introns from pre-mRNA. The megadalton-sized spliceosome is composed of four small nuclear RNPs and additional pre-mRNA splicing factors. The formation of an active spliceosome involves a series of regulated steps that...

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Bibliographic Details
Main Authors: Ohi, Melanie D., Ren, Liping, Wall, Joseph S., Gould, Kathleen L., Walz, Thomas
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805518/
https://ncbi.nlm.nih.gov/pubmed/17360628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611591104
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