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Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes

Excision of introns from pre-mRNAs is mediated by the spliceosome, a multi-megadalton complex consisting of U1, U2, U4/U6, and U5 snRNPs plus scores of associated proteins. Spliceosome assembly and disassembly are highly dynamic processes involving multiple stable intermediates. In this study, we ut...

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Detalhes bibliográficos
Main Authors: Chen, Weijun, Shulha, Hennady P., Ashar-Patel, Ami, Yan, Jing, Green, Karin M., Query, Charles C., Rhind, Nick, Weng, Zhiping, Moore, Melissa J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923126/
https://ncbi.nlm.nih.gov/pubmed/24442611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.040980.113
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