PEDF protects cardiomyocytes by promoting FUNDC1-mediated mitophagy via PEDF-R under hypoxic condition

Pigment epithelial-derived factor (PEDF) is known to exert diverse physiological activities. Previous studies suggest that hypoxia could induce mitophagy. Astoundingly, under hypoxic condition, we found that PEDF decreased the mitochondrial density of cardiomyocytes. In this study, we evaluated whet...

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Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Med
Egile Nagusiak: Li, Yufeng, Liu, Zhiwei, Zhang, Yiqian, Zhao, Qixiang, Wang, Xiaoyu, Lu, Peng, Zhang, Hao, Wang, Zhu, Dong, Hongyan, Zhang, Zhongming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: D.A. Spandidos 2018
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881750/
https://ncbi.nlm.nih.gov/pubmed/29512692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3536
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