PEDF regulates lipid metabolism and reduces apoptosis in hypoxic H9c2 cells by inducing autophagy related 5-mediated autophagy via PEDF-R

Pigment epithelial-derived factor (PEDF) is a multifunctional secreted glycoprotein, which exerts a variety of physiological activities. PEDF may protect against hypoxia-induced cell death associated with its antioxidative effects and p53 mitochondrial translocation in cultured cardiomyocytes and H9...

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Udgivet i:Mol Med Rep
Main Authors: Zhang, Yiqian, Li, Yufeng, Liu, Zhiwei, Zhao, Qixiang, Zhang, Hao, Wang, Xiaoyu, Lu, Peng, Yu, Hongli, Wang, Meng, Dong, Hongyan, Zhang, Zhongming
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928674/
https://ncbi.nlm.nih.gov/pubmed/29568944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8733
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