PEDF Inhibits the Activation of NLRP3 Inflammasome in Hypoxia Cardiomyocytes through PEDF Receptor/Phospholipase A2

The nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome has been linked to sterile inflammation, which is involved in ischemic injury in myocardial cells. Pigment epithelium-derived factor (PEDF) is a multifunctional secreted glycoprotein with many biological activ...

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Udgivet i:Int J Mol Sci
Main Authors: Zhou, Zhongxin, Wang, Zhu, Guan, Qiuhua, Qiu, Fan, Li, Yufeng, Liu, Zhiwei, Zhang, Hao, Dong, Hongyan, Zhang, Zhongming
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187864/
https://ncbi.nlm.nih.gov/pubmed/27973457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17122064
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