PKCα replaces AMPK to regulate mitophagy: Another PEDF role on ischaemic cardioprotection

Both decreased autophagy positive regulator AMP activated protein kinase (AMPK) level and promoted mitophagy are observed in oxygen‐glucose deprivation (OGD) cardiomyocytes treated with pigment epithelium‐derived factor (PEDF). This contradictory phenomenon and its underlying mechanisms have not bee...

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Pubblicato in:J Cell Mol Med
Autori principali: Miao, Haoran, Qiu, Fan, Huang, Bing, Liu, Xiucheng, Zhang, Hao, Liu, Zhiwei, Yuan, Yanliang, Zhao, Qixiang, Zhang, Hu, Dong, Hongyan, Zhang, Zhongming
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201373/
https://ncbi.nlm.nih.gov/pubmed/30230261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13849
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