Nalaganje...
Cyclic mechanical tension reinforces DNA damage and activates the p53-p21-Rb pathway to induce premature senescence of nucleus pulposus cells
Intervertebral disc (IVD) degeneration (IDD) is a widely recognized contributor to low back pain. Mechanical stress is a crucial etiological factor of IDD. During the process of IDD, a vicious circle is formed between abnormal mechanical stress and the damage of disc structure and function. Notably,...
Shranjeno v:
| izdano v: | Int J Mol Med |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
D.A. Spandidos
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881642/ https://ncbi.nlm.nih.gov/pubmed/29512682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3522 |
| Oznake: |
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