Inhibition of the P53/P21 Pathway Attenuates the Effects of Senescent Nucleus Pulposus Cell‐Derived Exosomes on the Senescence of Nucleus Pulposus Cells

OBJECTIVE: The purpose of this paper is to investigate the effects of senescent nucleus pulposus cell (NPC)‐derived exosomes (SNPC‐Exo) and the roles of the P53/P21 pathway on the senescence of NPC. METHODS: The senescent phenotypes of NPC were induced by interleukin‐1β treatment. SNPC‐Exo was extra...

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Bibliografiska uppgifter
I publikationen:Orthop Surg
Huvudupphovsmän: Chen, Chang‐chun, Chen, Jing, Wang, Wen‐liang, Xie, Liang, Shao, Chuan‐qiang, Zhang, Yan‐xiang
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley & Sons Australia, Ltd 2020
Ämnen:
Scientific Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957423/
https://ncbi.nlm.nih.gov/pubmed/33314719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/os.12886
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