Caveolin-1 regulates oxidative stress-induced senescence in nucleus pulposus cells primarily via the p53/p21 signaling pathway in vitro

Previous studies have indicated that cellular senescence is a critical underlying mechanism of intervertebral disc degeneration. However, the precise mechanism by which cellular senescence accelerates disc degeneration has not been fully elucidated. Caveolin-1 has recently emerged as an important re...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Ding, Lei, Zeng, Qingmin, Wu, Jingping, Li, Defang, Wang, Houlei, Lu, Wei, Jiang, Zengxin, Xu, Guoxiong
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780011/
https://ncbi.nlm.nih.gov/pubmed/29039595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7789
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